Duodenal Cancer, What is it and where is it?

This disease is very rare, most people have no idea where their duodenum is and or what it does. Living with this type of cancer is very hard. The duodenum is attached to the pancreas and small bowel, it is a major organ that you cannot live without. The surgery to remove the middle section of the duodenum sometimes is found to late to remove the tumor because it invades blood vessels and wraps around them to suck the life out of your body. Research on how to treat this cancer is very little so that leaves us in the open field to try and figure out what roads do we take. If the cancer returns on the small amount of duodenum there is no way to remove it by surgery. Currently we have no chemotherapy or radiation to kill the cells out. I am very blessed to have found a yahoo e-group who are in the same boat as me. We share what we have learned, what foods bring on the horrible bout of pain after eating, and the everyday hell we live with. When people hear our stories they say oh you look so good. The outside does look good, it is the inside that is sick and tormented with waves of pain, nausea, and it drains our energy to where we have to stay in bed or rest in the recliner. Our lives have changed so much and my journey is to help others who are going through a cancer diagnoses. I hope you read this and let me know what your thoughts are.
Thanks,
Pennie Bickerstaff

Duodenal cancer
Classification and external resources
Endoscopic image of adenocarcinoma of duodenum seen in the post-bulbar duodenum.
ICD-10	C17.0
ICD-9	152.0
MeSH	D004379

Duodenal cancer is a cancer in the beginning section of the small intestine. It is relatively rare compared to gastric cancer and colorectal cancer. Its histology is usually adenocarcinoma. Familial adenomatous polyposis (FAP), Gardner Syndrome, Lynch Syndrome, Muir-Torre syndrome, Celiac sprue, Puetz-Jeghers, Crohn's Disease and Juvenile Polyposis Syndrome are risk factors for developing this cancer.^[1]
The duodenum is the first part of the small intestine. It is located between the stomach and the jejunum. After foods combine with stomach acid, they descend into the duodenum where they mix with bile from the gall bladder and digestive juices from the pancreas.

Duodenal Cancer is a rare tumor that occurs less than 1% compare to other cancers. This tumor affects the duodenum periampullary regions or the ampullary. Many of the Duodenal Cancer could be easily found at an early stage. This is because when the tumor occurs in the body then they could be easily noticed by the lymph nodes and adjacent structures.
EarlierDuodenal Cancer could be easily found out by the endoscopy without identifying the symptoms of the disease. A new type of cancer found recently that are found on the duodenal bulb. By using the gastrointestinal radiography, the cancer could be easily detected. In this article, the radiographic, clinical and pathologic detection of cancer is discussed.
Case Report of patients affected by Duodenal Cancer
An 85 year old man observed different health problems of iron-deficiency anemia, guaiacpositive stool and aporadic pain in the lower abdomen. The doctors treat the patient by using H2 receptor antagonists. The gastrointestinal radiography has found out the stalkless and a small bit of lobulated polyp at the lower part of the duodenal. This ulcer has the diameter of 1.3 cm that was distinct from pylorus. Later on doctors found a 1.5 cm polyp by doing endoscopy of the duodenal bulb. By performing endoscopic biopsy has revealed out a papillary adenocarcinoma.
During the surgery, a tiny lobulated polyp of 1.5 cm is observed in patient duodenal bulb. The treatment of the patient is done by using gastroduodenectomy . After the pathologic examination of the cut edges, the treatment has brought out the papillary adenocarcinoma that was present at the bottom of the duodenal bulb. This ulcer was detected as a mucosa, whereas the lymph nodes are not affected by this cancer.
After the treatment, the lesion was known pathologically as the Duodenal Mucosa Cancer.
Discussion:
Duodenal Cancer is uncommon, but yet it is responsible for small cancers from 45% to 65%. The tumors are found in duodenum due to the adenomatous polyps that was present beforehand. This cancer is generally found in periampullary regions or ampullary regions that are near to the duodenum. Sometimes, the tumors could also occur in other body parts.
The symptoms of the Duodenal Cancer are nausea, vomiting, epigastric pain or weight loss. Most of the diagnostic patients that have Duodenal Cancer suffer from poor prognosis that would reduce the survival rates by 5 year that ranges from 20%-40%. The other factors that hamper the survival rates in patients could be the presence or absence, depth of invasion, symptoms durations and distant or nodal metastases.
The advanced stage of the Duodenal Cancer is found as the ringe lesions, ulcerated or polyploidy. Earlier reports have not detected the Duodenal Cancer. These could only be found due to the radiography and by endoscopy. Other tumors could be found by the radiography referred as the polypeptide lesions. Both the type of the polyps looked smooth and rounded in shape. A common type among all these is the benign tumors. The barium studies have showed that the polyps having more than 1 cm diameter were the ulcerated or lobulated lesions.